Additively Manufactured Biodegradable Zn‐Based Porous Scaffolds to Suppress Osteosarcoma and Promote Osteogenesis (Adv. Mater. 3/2025)

Osteosarcoma The osteosarcoma postoperative therapy encountered challenges of tumor recurrence and extensive bone defects. In article number 2410589, Yufeng Zheng, Peng Wen, Dandan Xia, and co-workers report an 3D-printed biodegradable Zn-0.8Li scaffold with Gyroid unit for osteosarcoma post-surgery. After the structure design and composition selection, this scaffold exhibited favorable mechanical properties, optimally balanced the co-release of Zn2+ and Li+, thereby suppressing osteosarcoma and promoting osteogenesis.