研究论文
Synthesis and biological evaluation of novel SIPI-7623 derivatives as farnesoid X receptor (FXR) antagonists
Siyun Nian, Guoping Wang, Zheng-Li Jiang, Ying Xiao, Mohan Huang, Yihuan Zhou, Xiangduan Tan
Wenzhou Medical University Yangtze River Pharmaceutical Group (China) Zhejiang Taizhou Hospital Shanghai Institute of Pharmaceutical Industry
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逐年被引趋势
320
19
20
24
325
26
关键指标
8
被引次数 · OpenAlex
0.32
领域内被引倍数
同类平均 = 1
同类平均 = 1
前 35%
引用位次
同领域 · 同年份 · 同类型
同领域 · 同年份 · 同类型
20
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学术脉络
学科主题
生物医学Estrogen and related hormone effects
Inflammatory mediators and NSAID effects · Cholesterol and Lipid Metabolism
参考文献 20
Activation of the farnesoid X receptor attenuates triptolide-induced liver toxicity
被引 46Jing Jin, Xiaozhe Sun, Zhongxiang Zhao · Phytomedicine · 2015
Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists
被引 8Kebiao Song, Xing Xu, Peng Liu · Bioorganic & Medicinal Chemistry · 2015
Reductive acylation of α-keto azides derived from <scp>L</scp> -amino acids using N-protected <scp>L</scp> -aminothiocarboxylic S-acids
被引 22M. Anthony McKervey, Michael O’Sullivan, Peter L. Myers · Journal of the Chemical Society Chemical Communications · 1993
此处列出前 3 条
引用本文 8
Highly potent non-steroidal FXR agonists protostane-type triterpenoids: Structure-activity relationship and mechanism
被引 33Zhi‐Lin Luan, Xiaokui Huo, Peipei Dong · European Journal of Medicinal Chemistry · 2019
Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment
被引 12Yu Yang, Yu Zhao, Wenzhen Li · European Journal of Medicinal Chemistry · 2020
Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological evaluation
被引 6Xiaodong Dou, Tongyu Huo, Yameng Liu · European Journal of Medicinal Chemistry · 2024
按被引量排序，此处列出前 3 条