研究论文
Design, synthesis and FXR partial agonistic activity of anthranilic acid derivatives bearing aryloxy moiety as therapeutic agents for metabolic dysfunction-associated steatohepatitis
Cong Chen, Xianghui Zhou, Wa Cheng, Xin Li, Bing Zhang, Jiaojiao Tu, Jieyun Meng, Yanfen Peng 等 11 位
Guilin Medical University Guangzhou University Guilin University of Electronic Technology
来源Bioorganic Chemistry
年份2024
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逐年被引趋势
420
425
关键指标
4
被引次数 · OpenAlex
1.26
领域内被引倍数
同类平均 = 1
同类平均 = 1
前 18%
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同领域 · 同年份 · 同类型
同领域 · 同年份 · 同类型
52
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学术脉络
学科主题
生物医学Liver Disease Diagnosis and Treatment
Diet, Metabolism, and Disease · Liver Diseases and Immunity
参考文献 52
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
被引 1,369Mitsuhiro Watanabe, Sander M. Houten, Li Wang · Journal of Clinical Investigation · 2004
Identification of a nuclear receptor that is activated by farnesol metabolites
被引 1,201Barry M. Forman, Elizabeth C. Goode, Jasmine Chen · Cell · 1995
Extending the Structure–Activity Relationship of Anthranilic Acid Derivatives As Farnesoid X Receptor Modulators: Development of a Highly Potent Partial Farnesoid X Receptor Agonist
被引 53Daniel Merk, Christina Lamers, Khalil Ali Ahmad · Journal of Medicinal Chemistry · 2014
此处列出前 3 条
引用本文 4
FXR-targeted drug discovery: Recent advances and therapeutic perspectives
被引 11Qian Li, Z. Liu, Weidong Shang · European Journal of Medicinal Chemistry · 2025
Recent advances in small molecule design strategies against hepatic fibrosis
被引 1Heming Chen, Heming Chen, Wei Su · European Journal of Medicinal Chemistry · 2025
Discovery of novel 1-(4-aminophenylacetyl)piperidine derivatives as FXR partial agonists for the potential treatment of metabolic dysfunction-associated steatohepatitis
被引 0Bing Zhang, Jiaojiao Tu, Zhenghu Ban · European Journal of Medicinal Chemistry · 2025
按被引量排序，此处列出前 3 条