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RNA-Targeted Therapeutics
Stanley T. Crooke, Joseph L. Witztum, C. Frank Bennett, Brenda F. Baker
Ionis Pharmaceuticals (United States) University of California San Diego
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生物医学RNA Interference and Gene Delivery
RNA Research and Splicing · RNA modifications and cancer
参考文献 193
Toxicological and Pharmacokinetic Properties of QPI-1007, a Chemically Modified Synthetic siRNA Targeting Caspase 2 mRNA, Following Intravitreal Injection
被引 86Elisabeth C.R. Solano, Douglas J. Kornbrust, Amber Beaudry · Nucleic Acid Therapeutics · 2014
A Phase I Open Label, Dose Escalation Trial Of QPI-1007 Delivered By A Single Intravitreal (IVT) Injection To Subjects With Low Visual Acuity And Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
被引 8Andrew N. Antoszyk, Bradley J. Katz, Rishi P. Singh · 2013
Phase 2 of bamosiran (SYL040012), a novel RNAi based compound for the treatment of increased intraocular pressure associated to glaucoma
被引 16Victoria González, Kadi Palumaa, Krista Turman · 2014
此处列出前 3 条
施引文献 806
Therapeutic siRNA: state of the art
被引 1,537Bo Hu, Liping Zhong, Yuhua Weng · Signal Transduction and Targeted Therapy · 2020
Circular RNAs: Characterization, cellular roles, and applications
被引 1,128Chu‐Xiao Liu, Ling‐Ling Chen · Cell · 2022
Lipoprotein(a) Reduction in Persons with Cardiovascular Disease
被引 1,027Sotirios Tsimikas, Ewa Karwatowska‐Prokopczuk, Ioanna Gouni‐Berthold · New England Journal of Medicine · 2020
按被引量排序,此处列出前 3 条