研究论文

Discovery of novel ocotillol derivatives modulating glucocorticoid receptor/NF-κB signaling for the treatment of sepsis

Gongshan Ma, Xiaojin Gao, Xin Zhang, Xin Zhang, Haixia Li, Zhiyuan Geng, Jing Gao, Shuxin Yang 等 14 位

Yantai University　Binzhou Medical University

来源European Journal of Medicinal Chemistry

年份2024

DOI10.1016/j.ejmech.2024.116427

原文https://doi.org/10.1016/j.ejmech.2024.116427

阅读操作

确认中

在文库中上传 PDF 后可生成中文音频讲解。

摘要与影响

摘要 · 节选

暂未获取摘要。可打开原文或 PDF，后续可基于全文生成更完整的速读。

逐年被引趋势

420

426

关键指标

被引次数 · OpenAlex

0.72

领域内被引倍数
同类平均 = 1

前 34%

引用位次
同领域 · 同年份 · 同类型

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

Immune Response and Inflammation

Pharmacological Effects of Natural Compounds · NF-κB Signaling Pathways

参考文献 51

Glucocorticoid Repression of Inflammatory Gene Expression Shows Differential Responsiveness by Transactivation- and Transrepression-Dependent Mechanisms

Elizabeth M. King, Joanna E. Chivers, Christopher Francis Rider · PLoS ONE · 2013

被引 95

The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin‐induced lethal shock

Chul‐Su Yang, Sung‐Ryong Ko, Byung-Goo Cho · Journal of Cellular and Molecular Medicine · 2008

被引 77

Anti-inflammatory effects of escin are correlated with the glucocorticoid receptor/NF-κB signaling pathway, but not the COX/PGF2α signaling pathway

Hongsheng Wang, LEIMING ZHANG, Na Jiang · Experimental and Therapeutic Medicine · 2013

被引 42

此处列出前 3 条

引用本文 5

Discovery of novel fusidic acid derivatives in mitigating LPS-induced acute liver injury by modulating RIPK1

Jing Gao, Zhiyuan Geng, Hui Jun Yang · Bioorganic & Medicinal Chemistry Letters · 2025

被引 2

Severity and 28-day in-hospital mortality of interleukin-6, neutrophil to lymphocyte ratio, and APACHE II score in patients with sepsis

SHENG Yue, Xiaojing Du, X. Li · Frontiers in Cellular and Infection Microbiology · 2026

被引 0

Mechanistic insights into mitigation of sepsis-induced acute lung injury by quercitrin via TLR4/MAPK pathway inhibition

Qian Sang, Chunhua Cai, Xiaoxiao Lu · Journal of Pharmacy and Pharmacology · 2026

被引 0

按被引量排序，此处列出前 3 条

研究论文

Discovery of novel ocotillol derivatives modulating glucocorticoid receptor/NF-κB signaling for the treatment of sepsis

Gongshan Ma, Xiaojin Gao, Xin Zhang, Xin Zhang, Haixia Li, Zhiyuan Geng, Jing Gao, Shuxin Yang 等 14 位

Yantai University　Binzhou Medical University

来源European Journal of Medicinal Chemistry

年份2024

DOI10.1016/j.ejmech.2024.116427

原文https://doi.org/10.1016/j.ejmech.2024.116427

阅读操作

确认中

在文库中上传 PDF 后可生成中文音频讲解。

摘要与影响

摘要 · 节选

暂未获取摘要。可打开原文或 PDF，后续可基于全文生成更完整的速读。

逐年被引趋势

420

426

关键指标

被引次数 · OpenAlex

0.72

领域内被引倍数
同类平均 = 1

前 34%

引用位次
同领域 · 同年份 · 同类型

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

Immune Response and Inflammation

Pharmacological Effects of Natural Compounds · NF-κB Signaling Pathways

参考文献 51

Glucocorticoid Repression of Inflammatory Gene Expression Shows Differential Responsiveness by Transactivation- and Transrepression-Dependent Mechanisms

Elizabeth M. King, Joanna E. Chivers, Christopher Francis Rider · PLoS ONE · 2013

被引 95

The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin‐induced lethal shock

Chul‐Su Yang, Sung‐Ryong Ko, Byung-Goo Cho · Journal of Cellular and Molecular Medicine · 2008

被引 77

Anti-inflammatory effects of escin are correlated with the glucocorticoid receptor/NF-κB signaling pathway, but not the COX/PGF2α signaling pathway

Hongsheng Wang, LEIMING ZHANG, Na Jiang · Experimental and Therapeutic Medicine · 2013

被引 42

此处列出前 3 条

引用本文 5

Discovery of novel fusidic acid derivatives in mitigating LPS-induced acute liver injury by modulating RIPK1

Jing Gao, Zhiyuan Geng, Hui Jun Yang · Bioorganic & Medicinal Chemistry Letters · 2025

被引 2

Severity and 28-day in-hospital mortality of interleukin-6, neutrophil to lymphocyte ratio, and APACHE II score in patients with sepsis

SHENG Yue, Xiaojing Du, X. Li · Frontiers in Cellular and Infection Microbiology · 2026

被引 0

Mechanistic insights into mitigation of sepsis-induced acute lung injury by quercitrin via TLR4/MAPK pathway inhibition

Qian Sang, Chunhua Cai, Xiaoxiao Lu · Journal of Pharmacy and Pharmacology · 2026

被引 0

按被引量排序，此处列出前 3 条