研究论文
Design, synthesis, and biological evaluation of C-12 modified ocotillol-type derivatives as novel P-glycoprotein modulators for overcoming multidrug resistance
Cheng Chen, Ziqian Hao, Jiaxuan Chen, Shuang Li, Yuxin Su, Suwei Jiang, Lin Ma, Hanqi Lv 等 12 位
Yantai University
来源European Journal of Medicinal Chemistry
年份2025
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逐年被引趋势
210
25
226
关键指标
3
被引次数 · OpenAlex
1.91
领域内被引倍数
同类平均 = 1
同类平均 = 1
前 14%
引用位次
同领域 · 同年份 · 同类型
同领域 · 同年份 · 同类型
43
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学术脉络
学科主题
生物医学Drug Transport and Resistance Mechanisms
Cancer therapeutics and mechanisms · Natural product bioactivities and synthesis
参考文献 43
Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents
被引 42Yunkai Zhang, Hengyuan Zhang, Guan-Nan Zhang · Oncotarget · 2015
Targeting the Achilles Heel of Multidrug-Resistant Cancer by Exploiting the Fitness Cost of Resistance
被引 207Gergely Szakács, Matthew D. Hall, Michael M. Gottesman · Chemical Reviews · 2014
P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives
被引 392Ziyad Binkhathlan, Afsaneh Lavasanifar · Current Cancer Drug Targets · 2013
此处列出前 3 条
施引文献 3
Pyxinol derivative suppresses LPS-induced inflammation by targeting the p65-p50 heterodimer
被引 2Xuwen Luan, Zongji Zou, Jiaxuan Chen · Bioorganic Chemistry · 2025
Discovery of novel 20S-protopanaxadiol derivatives in alleviating sepsis-associated liver injury by modulating p65/p50 activity
被引 0Ziqian Hao, Xuwen Luan, Xiaoliang Mi · European Journal of Medicinal Chemistry · 2026
Protein Engineering to Change the Sugar Donor and Improve the Activity of PnUGT94Q39 for Efficient Ginsenoside Rf Biosynthesis
被引 0Maoqi Hou, S H Chen, L Yang · Journal of Agricultural and Food Chemistry · 2026
按被引量排序，此处列出前 3 条