研究论文
Understanding the activation mechanism of GLP-1R/GIPR by dual agonist Tirzepatide via molecular dynamics and protein-peptide binding
Xuejun Zou, Yu He, Ya Gao, Jian Wang, John Z. H. Zhang
East China Normal University Shanghai University of Engineering Science Beike Biotechnology (China) New York University Shanghai
来源International Journal of Biological Macromolecules
年份2025
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逐年被引趋势
530
526
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5
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3.35
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同类平均 = 1
同类平均 = 1
前 7%
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生物医学Diabetes Treatment and Management
Drug Transport and Resistance Mechanisms · Receptor Mechanisms and Signaling
参考文献 50
The structure and function of the glucagon‐like peptide‐1 receptor and its ligands
被引 285Dan Donnelly · British Journal of Pharmacology · 2011
Generic GPCR residue numbers – aligning topology maps while minding the gaps
被引 514Vignir Ísberg, Chris de Graaf, Andrea Bortolato · Trends in Pharmacological Sciences · 2014
Generalized Born Model with a Simple, Robust Molecular Volume Correction
被引 457John Mongan, Carlos Simmerling, J. Andrew McCammon · Journal of Chemical Theory and Computation · 2006
此处列出前 3 条
引用本文 5
Research progress on oral glucagon-like peptide-1 receptor agonists in the treatment of diabetes mellitus type 2
被引 4Qian Shao, Juan Xiong, Jing Cynthia Wu · Frontiers in Molecular Biosciences · 2026
Advancing precision tumor therapy: Progress in targeted delivery of peptide-based nanomaterials from microenvironment to organelles
被引 1Kexin Tian, Jiabao Sheng, Jiao Chen · Materials Today Bio · 2026
Current diabetes drugs: Lessons learned and implications for next-generation therapeutics
被引 0Jiayu Liao, Zhaotong Cong, Ke Liu · The Innovation Drug Discovery · 2026
按被引量排序，此处列出前 3 条