研究论文

Lactate exacerbated rheumatoid arthritis by activating the cGAS-STING signaling pathway in macrophages

Yan Zhang, Chunhua Yin, Xiaoling Yuan, Shu Xu

Soochow University

来源International Immunopharmacology

年份2025

DOI10.1016/j.intimp.2025.115993

原文https://doi.org/10.1016/j.intimp.2025.115993

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逐年被引趋势

740

726

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2.21

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学术脉络

学科主题

生物医学

interferon and immune responses

NF-κB Signaling Pathways · Immune responses and vaccinations

参考文献 29

Metabolic signatures of T-cells and macrophages in rheumatoid arthritis

Cornelia M. Weyand, Markus Zeisbrich, Jörg J. Goronzy · Current Opinion in Immunology · 2017

被引 152

Apoptosis-derived membrane vesicles drive the cGAS–STING pathway and enhance type I IFN production in systemic lupus erythematosus

Yasuhiro Kato, JeongHoon Park, Hyota Takamatsu · Annals of the Rheumatic Diseases · 2018

被引 311

Lactate transporters as therapeutic targets in cancer and inflammatory diseases

Valentina Pucino, Danilo Cucchi, Claudio Mauro · Expert Opinion on Therapeutic Targets · 2018

被引 83

此处列出前 3 条

引用本文 7

Metabolic-epigenetic rewiring in rheumatoid arthritis: from pathogenic memory to precision restoration

Shu Li, Lei Wan, Kun Wang · Frontiers in Immunology · 2026

被引 2

The emerging role of lactate in skeletal homeostasis and disorders: Integrated mechanisms and translational opportunities

Boyi Zong, Fengzhi Yu, Shichang Li · Journal of Orthopaedic Translation · 2026

被引 1

Engineered Mitochondria-Targeted Biomimetic Hybrid Nanovesicles Ameliorate Rheumatoid Arthritis via Regulating Macrophage Autophagy and cGAS-STING Signaling

Li Lu, Yong Su, Lisong Zheng · ACS Applied Materials & Interfaces · 2026

被引 0

按被引量排序，此处列出前 3 条