研究论文
A sensitive and drug tolerant assay for detecting anti-AAV9 antibodies using affinity capture elution
Emma Simmons, Yi Wen, Jingling Li, Yuewei Qian, Li Chin Wong, Robert J. Konrad, Nicoletta Bivi
Eli Lilly (United States)
来源Journal of Immunological Methods
年份2022
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生物医学Virus-based gene therapy research
Viral Infections and Immunology Research · CAR-T cell therapy research
参考文献 47
An Affinity Capture Elution (ACE) assay for detection of anti-drug antibody to monoclonal antibody therapeutics in the presence of high levels of drug
被引 156James S. Bourdage, Carolyn A. Cook, Daphne L. Farrington · Journal of Immunological Methods · 2007
Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B
被引 1,259Amit Nathwani, Ulreke M. Reiss, Edward G. D. Tuddenham · New England Journal of Medicine · 2014
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
被引 2,148Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda · Nature Medicine · 2006
此处列出前 3 条
引用本文 11
Comparison of Pre-existing Anti-AAV8 Total Antibody Screening and Confirmatory Assays with a Cell-Based Neutralizing Assay in Normal Human Serum
被引 12Yan‐Shan Dai, Huijin Dong, Carol Gleason · The AAPS Journal · 2023
Essential role of pre-existing humoral immunity in TLR9-mediated type I IFN response to recombinant AAV vectors in human whole blood
被引 9Nada S. Alakhras, Christopher A. Moreland, Li Chin Wong · Frontiers in Immunology · 2024
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control
被引 5Uwe Wessels, Florian Neff, Julia Fakhiri · Bioanalysis · 2024
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