研究论文开放获取

iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders

Hideyuki Okano, Satoru Morimoto

Keio University　RIKEN Center for Brain Science

来源Cell stem cell

年份2022

DOI10.1016/j.stem.2022.01.007

原文https://doi.org/10.1016/j.stem.2022.01.007

阅读操作

确认中

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摘要与影响

摘要 · 节选

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逐年被引趋势

65330

6524

关键指标

202

被引次数 · OpenAlex

12.58

领域内被引倍数
同类平均 = 1

前 0.5%

引用位次
同领域 · 同年份 · 同类型

216

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

Pluripotent Stem Cells Research

Alzheimer's disease research and treatments · Neurogenesis and neuroplasticity mechanisms

参考文献 216

100 Years of Alzheimer's disease (1906–2006)

J. Manuel Martínez Lage · Journal of Alzheimer s Disease · 2006

被引 51

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

Jérôme Mertens, Apuã C.M. Paquola, Manching Ku · Cell stem cell · 2015

被引 763

I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway

Etsuro Ohta, Tomoko Nihira, Akiko Uchino · Human Molecular Genetics · 2015

被引 70

此处列出前 3 条

引用本文 202

Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications

Jonas Cerneckis, Hongxia Cai, Yanhong Shi · Signal Transduction and Targeted Therapy · 2024

被引 431

Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

Matin Chehelgerdi, Fereshteh Behdarvand Dehkordi, Mohammad Chehelgerdi · Molecular Cancer · 2023

被引 175

A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population

Shinsuke Yoshida, Tomoaki Kato, Yoshiko Sato · Med · 2022

被引 134

按被引量排序，此处列出前 3 条

研究论文开放获取

iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders

Hideyuki Okano, Satoru Morimoto

Keio University　RIKEN Center for Brain Science

来源Cell stem cell

年份2022

DOI10.1016/j.stem.2022.01.007

原文https://doi.org/10.1016/j.stem.2022.01.007

阅读操作

确认中

在文库中上传 PDF 后可生成中文音频讲解。

摘要与影响

摘要 · 节选

暂未获取摘要。可打开原文或 PDF，后续可基于全文生成更完整的速读。

逐年被引趋势

65330

6524

关键指标

202

被引次数 · OpenAlex

12.58

领域内被引倍数
同类平均 = 1

前 0.5%

引用位次
同领域 · 同年份 · 同类型

216

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

Pluripotent Stem Cells Research

Alzheimer's disease research and treatments · Neurogenesis and neuroplasticity mechanisms

参考文献 216

100 Years of Alzheimer's disease (1906–2006)

J. Manuel Martínez Lage · Journal of Alzheimer s Disease · 2006

被引 51

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

Jérôme Mertens, Apuã C.M. Paquola, Manching Ku · Cell stem cell · 2015

被引 763

I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway

Etsuro Ohta, Tomoko Nihira, Akiko Uchino · Human Molecular Genetics · 2015

被引 70

此处列出前 3 条

引用本文 202

Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications

Jonas Cerneckis, Hongxia Cai, Yanhong Shi · Signal Transduction and Targeted Therapy · 2024

被引 431

Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

Matin Chehelgerdi, Fereshteh Behdarvand Dehkordi, Mohammad Chehelgerdi · Molecular Cancer · 2023

被引 175

A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population

Shinsuke Yoshida, Tomoaki Kato, Yoshiko Sato · Med · 2022

被引 134

按被引量排序，此处列出前 3 条