研究论文

Targeting methionine metabolism in cancer: opportunities and challenges

Peng Bin, Chuanlong Wang, Hangchao Zhang, Yuqi Yan, Wenkai Ren

South China Agricultural University　Shaoguan University

来源Trends in Pharmacological Sciences

年份2024

DOI10.1016/j.tips.2024.03.002

原文https://doi.org/10.1016/j.tips.2024.03.002

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摘要与影响

摘要 · 节选

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逐年被引趋势

1260

1225

关键指标

被引次数 · OpenAlex

8.29

领域内被引倍数
同类平均 = 1

前 2%

引用位次
同领域 · 同年份 · 同类型

115

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

Cancer Research and Treatments

Cancer, Hypoxia, and Metabolism · Amino Acid Enzymes and Metabolism

参考文献 115

High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.

Robert M. Hoffman, Richard W. Erbe · Proceedings of the National Academy of Sciences · 1976

被引 299

The landscape of somatic copy-number alteration across human cancers

Rameen Beroukhim, Craig H. Mermel, Dale Porter · Nature · 2010

被引 4,181

<i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth · Science · 2016

被引 668

此处列出前 3 条

引用本文 34

Unveiling the crossroads of STING signaling pathway and metabolic reprogramming: the multifaceted role of the STING in the TME and new prospects in cancer therapies

Siwei Wang, Qin Lu, Furong Liu · Cell Communication and Signaling · 2025

被引 21

Metabolic reprogramming of tumor microenviroment by engineered bacteria

Heng Wang, Heng Wang, Fang Xu · Seminars in Cancer Biology · 2025

被引 15

DNA-Binding Agent Trabectedin Combined With Recombinant Methioninase Is Synergistic to Decrease Fibrosarcoma Cell Viability and Induce Nuclear Fragmentation But Not Synergistic on Normal Fibroblasts

Sei Morinaga, Qinghong Han, Yutaro Kubota · Anticancer Research · 2024

被引 10

按被引量排序，此处列出前 3 条

研究论文

Targeting methionine metabolism in cancer: opportunities and challenges

Peng Bin, Chuanlong Wang, Hangchao Zhang, Yuqi Yan, Wenkai Ren

South China Agricultural University　Shaoguan University

来源Trends in Pharmacological Sciences

年份2024

DOI10.1016/j.tips.2024.03.002

原文https://doi.org/10.1016/j.tips.2024.03.002

阅读操作

确认中

在文库中上传 PDF 后可生成中文音频讲解。

摘要与影响

摘要 · 节选

暂未获取摘要。可打开原文或 PDF，后续可基于全文生成更完整的速读。

逐年被引趋势

1260

1225

关键指标

被引次数 · OpenAlex

8.29

领域内被引倍数
同类平均 = 1

前 2%

引用位次
同领域 · 同年份 · 同类型

115

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

Cancer Research and Treatments

Cancer, Hypoxia, and Metabolism · Amino Acid Enzymes and Metabolism

参考文献 115

High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.

Robert M. Hoffman, Richard W. Erbe · Proceedings of the National Academy of Sciences · 1976

被引 299

The landscape of somatic copy-number alteration across human cancers

Rameen Beroukhim, Craig H. Mermel, Dale Porter · Nature · 2010

被引 4,181

<i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth · Science · 2016

被引 668

此处列出前 3 条

引用本文 34

Unveiling the crossroads of STING signaling pathway and metabolic reprogramming: the multifaceted role of the STING in the TME and new prospects in cancer therapies

Siwei Wang, Qin Lu, Furong Liu · Cell Communication and Signaling · 2025

被引 21

Metabolic reprogramming of tumor microenviroment by engineered bacteria

Heng Wang, Heng Wang, Fang Xu · Seminars in Cancer Biology · 2025

被引 15

DNA-Binding Agent Trabectedin Combined With Recombinant Methioninase Is Synergistic to Decrease Fibrosarcoma Cell Viability and Induce Nuclear Fragmentation But Not Synergistic on Normal Fibroblasts

Sei Morinaga, Qinghong Han, Yutaro Kubota · Anticancer Research · 2024

被引 10

按被引量排序，此处列出前 3 条