Utilization of Electric Fields to Modulate Molecular Activities on the Nanoscale: From Physical Properties to Chemical Reactions

As a primary energy source, electricity drives broad fields from everyday electronic circuits to industrial chemical catalysis. From a chemistry viewpoint, studying electric field effects on chemical reactivity is highly important for revealing the intrinsic mechanisms of molecular behaviors and mastering chemical reactions. Recently, manipulating the molecular activity using electric fields has emerged as a new research field. In addition, because integration of molecules into electronic devices has the natural complementary metal-oxide-semiconductor compatibility, electric field-driven molecular devices meet the requirements for both electronic device miniaturization and precise regulation of chemical reactions. This Review provides a timely and comprehensive overview of recent state-of-the-art advances, including theoretical models and prototype devices for electric field-based manipulation of molecular activities. First, we summarize the main approaches to providing electric fields for molecules. Then, we introduce several methods to measure their strengths in different systems quantitatively. Subsequently, we provide detailed discussions of electric field-regulated photophysics, electron transport, molecular movements, and chemical reactions. This review intends to provide a technical manual for precise molecular control in devices via electric fields. This could lead to development of new optoelectronic functions, more efficient logic processing units, more precise bond-selective control, new catalytic paradigms, and new chemical reactions.