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PI3K/Akt: getting it right matters
T F Franke
New York University
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学科主题
生物医学PI3K/AKT/mTOR signaling in cancer
Polyamine Metabolism and Applications · Cancer Mechanisms and Therapy
参考文献 234
Insulin stimulates the kinase activity of RAC‐PK, a pleckstrin homology domain containing ser/thr kinase.
被引 361Aimee D. Kohn, Kristina S. Kovacina, Richard A. Roth · The EMBO Journal · 1995
Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications.
被引 176Alfonso Bellacosa, T F Franke, María Eugenia González · PubMed · 1993
The SH2-like Akt homology (AH) domain of c-akt is present in multiple copies in the genome of vertebrate and invertebrate eucaryotes. Cloning and characterization of the Drosophila melanogaster c-akt homolog Dakt1.
被引 52T F Franke, K D Tartof, P N Tsichlis · PubMed · 1994
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施引文献 690
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
被引 2,967Silvana Konermann, Mark D. Brigham, Alexandro E. Trevino · Nature · 2014
A circadian gene expression atlas in mammals: Implications for biology and medicine
被引 2,413Ray Zhang, Nicholas F. Lahens, Heather Ballance · Proceedings of the National Academy of Sciences · 2014
TGF-β signaling in health, disease and therapeutics
被引 1,048Ziqin Deng, Tao Fan, Xiao Chu · Signal Transduction and Targeted Therapy · 2024
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