Author Correction: AAV-based delivery of RNAi targeting ataxin-2 improves survival and pathology in TDP-43 mice
Defne A. Amado, Ashley B. Robbins, Katherine R. Whiteman, Alicia R. Smith, Guillem Chillon, Yonghong Chen, Joshua A. K. Fuller, Nicholas A. Patty 等 15 位
Children's Hospital of Philadelphia University of Pennsylvania New York University
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In the version of the article initially published, a reference citation was missing in the first sentence of the Results “Translatability to human targets” section, which now reads “To determine the ability of miAtxn2 to target human ATXN2, we used the 127Q transgenic mouse model of spinocerebellar ataxia type 2, in which mice overexpress mutant human ATXN2 in cerebellar Purkinje cells [Hansen, S.T. et al. Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. Hum. Mol. Genet . 22 , 271–283 (2013)].” The reference is now included in the HTML and PDF versions of the article.
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生物医学RNA Interference and Gene Delivery
Amyotrophic Lateral Sclerosis Research · Genetic Neurodegenerative Diseases
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