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PROTAC targeted protein degraders: the past is prologue
Miklós Békés, David R. Langley, Craig M. Crews
Arvinas (United States) Yale University
来源Nature Reviews Drug Discovery
年份2022
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学术脉络
学科主题
生物医学Protein Degradation and Inhibitors
Ubiquitin and proteasome pathways · Peptidase Inhibition and Analysis
参考文献 257
Mechanisms of Action of the Novel Sulfonamide Anticancer Agent E7070 on Cell Cycle Progression in Human Non-Small Cell Lung Cancer Cells
被引 114Kazuya Fukuoka, Jitsuo Usuda, Yasuo Iwamoto · Investigational New Drugs · 2001
The MAGE protein family and cancer
被引 275Jenny L. Weon, Patrick Ryan Potts · Current Opinion in Cell Biology · 2015
Catalytic in vivo protein knockdown by small-molecule PROTACs
被引 1,363Daniel P. Bondeson, Alina Mares, Ian E. Smith · Nature Chemical Biology · 2015
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An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)
被引 985Christopher M. Marshall, John G. Federice, Chloe N. Bell · Journal of Medicinal Chemistry · 2024
Targeted protein degradation: mechanisms, strategies and application
被引 964Lin Zhao, Jia Zhao, Kunhong Zhong · Signal Transduction and Targeted Therapy · 2022
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