研究论文
In vivo chimeric antigen receptor (CAR)-T cell therapy
Adrian Bot, Andrew M. Scharenberg, Kevin M. Friedman, Lin T. Guey, Robert Hofmeister, James I. Andorko, Michael Klichinsky, Frank Neumann 等 15 位
Child Abuse Prevention Services of Tuscaloosa Q Therapeutics (United States) Moderna Therapeutics (United States) Integrated BioTherapeutics (United States)
来源Nature Reviews Drug Discovery
年份2025
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学术脉络
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生物医学CAR-T cell therapy research
Biomedical and Engineering Education · Biomedical Ethics and Regulation
参考文献 177
Chimeric Receptors Providing Both Primary and Costimulatory Signaling in T Cells from a Single Gene Product
被引 545Helene M. Finney, Alastair D. G. Lawson, Christopher Bebbington · The Journal of Immunology · 1998
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
被引 1,343James N. Kochenderfer, Wyndham H. Wilson, John E. Janik · Blood · 2010
Direct gene transfer into muscle
被引 103István Dankó, Jon A. Wolff · Vaccine · 1994
此处列出前 3 条
引用本文 89
The Current Landscape of Modular CAR T Cells
被引 7Alexander Haide Joechner, Melanie Mach, Ziduo Li · International Journal of Molecular Sciences · 2025
In vivo CAR-cell therapy: current challenges and emerging therapeutic advances
被引 6Yi-Min Yang, Bo Bao, Yu-Hao Cao · Molecular Biomedicine · 2026
ApoE2-DARPin fusion proteins enable selective RNA transfer to CD8 T cells by lipid nanoparticles
被引 5Samuel A. Theuerkauf, Luca J. Zinser, Nandini Sheth · Journal of Controlled Release · 2025
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