研究论文

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer

Jackson Liang, Xiaosai Yao, Patrick Aouad, Bu-Er Wang, Lisa Crocker, Subhra Chaudhuri, Yuxin Liang, Spyros Darmanis 等 16 位

Translational Research in Oncology　Genesys (United States)

来源Nature Cancer

年份2025

DOI10.1038/s43018-024-00898-8

原文https://doi.org/10.1038/s43018-024-00898-8

阅读操作

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摘要与影响

摘要 · 节选

暂未获取摘要。可打开原文或 PDF，后续可基于全文生成更完整的速读。

逐年被引趋势

1050

1026

关键指标

被引次数 · OpenAlex

13.58

领域内被引倍数
同类平均 = 1

前 0.9%

引用位次
同领域 · 同年份 · 同类型

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

BRCA gene mutations in cancer

Genomics and Chromatin Dynamics · Cancer-related Molecular Pathways

参考文献 59

Regulation of Estrogen Receptor Messenger Ribonucleic Acid and Protein Levels in Human Breast Cancer Cell Lines by Sex Steroid Hormones, Their Antagonists, and Growth Factors

Linnea D. Read, Geoffrey L. Greene, Benita S. Katzenellenbogen · Molecular Endocrinology · 1989

被引 262

Molecular signatures database (MSigDB) 3.0

Arthur Liberzon, Aravind Subramanian, Reid M. Pinchback · Bioinformatics · 2011

被引 7,928

Concentrations of circulating steroids in normal prepubertal and adult male and female humans, chimpanzees, rhesus monkeys, rats, mice, and hamsters: A literature survey

James Overpeck, Sylvia H. Colson, John R. Hohmann · Journal of Toxicology and Environmental Health · 1978

被引 91

此处列出前 3 条

引用本文 16

Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance

Patrick Aouad, Karim Halabi, Berthe Hayar · npj Breast Cancer · 2026

被引 5

Tumor Cell Plasticity in Cancer: Signaling Pathways and Pharmaceutical Interventions

Shangwei Sun, Yunwei Sun, Lan Ling · MedComm · 2025

被引 4

Loss of luminal lineage drives resistance to next-generation ERα antagonists in pretreated ER+ HER2− locally-advanced or metastatic breast cancer

Jackson Liang, Christy C. Ong, Kareem A. Heslop · Nature Communications · 2026

被引 2

按被引量排序，此处列出前 3 条

研究论文

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer

Jackson Liang, Xiaosai Yao, Patrick Aouad, Bu-Er Wang, Lisa Crocker, Subhra Chaudhuri, Yuxin Liang, Spyros Darmanis 等 16 位

Translational Research in Oncology　Genesys (United States)

来源Nature Cancer

年份2025

DOI10.1038/s43018-024-00898-8

原文https://doi.org/10.1038/s43018-024-00898-8

阅读操作

确认中

在文库中上传 PDF 后可生成中文音频讲解。

摘要与影响

摘要 · 节选

暂未获取摘要。可打开原文或 PDF，后续可基于全文生成更完整的速读。

逐年被引趋势

1050

1026

关键指标

被引次数 · OpenAlex

13.58

领域内被引倍数
同类平均 = 1

前 0.9%

引用位次
同领域 · 同年份 · 同类型

参考文献

Google Scholar 与 OpenAlex 的被引统计范围不同，数值存在差异属正常。

AI 辅助阅读

依据：文献信息

论文问答

当前基于文献信息回答

可就本文提问；依据不足时会说明。

学术脉络

学科主题

生物医学

BRCA gene mutations in cancer

Genomics and Chromatin Dynamics · Cancer-related Molecular Pathways

参考文献 59

Regulation of Estrogen Receptor Messenger Ribonucleic Acid and Protein Levels in Human Breast Cancer Cell Lines by Sex Steroid Hormones, Their Antagonists, and Growth Factors

Linnea D. Read, Geoffrey L. Greene, Benita S. Katzenellenbogen · Molecular Endocrinology · 1989

被引 262

Molecular signatures database (MSigDB) 3.0

Arthur Liberzon, Aravind Subramanian, Reid M. Pinchback · Bioinformatics · 2011

被引 7,928

Concentrations of circulating steroids in normal prepubertal and adult male and female humans, chimpanzees, rhesus monkeys, rats, mice, and hamsters: A literature survey

James Overpeck, Sylvia H. Colson, John R. Hohmann · Journal of Toxicology and Environmental Health · 1978

被引 91

此处列出前 3 条

引用本文 16

Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance

Patrick Aouad, Karim Halabi, Berthe Hayar · npj Breast Cancer · 2026

被引 5

Tumor Cell Plasticity in Cancer: Signaling Pathways and Pharmaceutical Interventions

Shangwei Sun, Yunwei Sun, Lan Ling · MedComm · 2025

被引 4

Loss of luminal lineage drives resistance to next-generation ERα antagonists in pretreated ER+ HER2− locally-advanced or metastatic breast cancer

Jackson Liang, Christy C. Ong, Kareem A. Heslop · Nature Communications · 2026

被引 2

按被引量排序，此处列出前 3 条