Phenylene vinylene macrocycles as artificial transmembrane transporters
Xinyu Hu, Chao Yu, Kenji D. Okochi, Yinghua Jin, Zhenning Liu, Wei Zhang
University of Colorado Boulder Jilin University Jilin Medical University University of Colorado System
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摘要与影响
A series of rigid phenylene vinylene macrocycles and phenylene ethynylene macrocycles with various substituents have been investigated as transmembrane ion channels. The length and polarity of the substituents have a significant effect on the ion channel formation and the mass transport efficiency. Macrocycles with strong aggregation facilitate ion passage across lipid bilayers.
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学术脉络
学科主题
化学Molecular Sensors and Ion Detection
Supramolecular Chemistry and Complexes · Lipid Membrane Structure and Behavior
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