Modern organic transformations: heterogeneous thermocatalysis or photocatalysis?

Organic transformation driven by heterogeneous catalysis is of crucial significance in both fundamental research and modern industrial production of fine chemicals. Thermocatalysis offers excellent applications due to its high activity and excellent scalability, yet still faces significant challenges toward the goals of high efficiency, energy-saving and sustainability. Recently, photocatalysis has emerged as a promising alternative for addressing these issues in a green and economical manner. In practice, the selection of an appropriate catalytic system is a critical factor that can influence the chemical process on multiple levels significantly. In this review, we aim to present a tutorial demonstration about the critical comparison between thermo- and photocatalytic terms for organic transformation. We begin by outlining the basic principles in thermo- and photocatalytic fundamentals, together with summarizing the general advantages and disadvantages of each. Subsequently, given the high sustainability and potentiality exhibited by the photocatalytic process, we present its representative applications including oxidation, reduction, coupling, and cleavage series. The general reaction conditions and activities observed in thermocatalysis for similar reactions are also introduced for comparison. The understanding of reaction mechanisms and the resulting regulations toward activity and selectivity are specifically discussed. Finally, future perspectives of heterogeneous photocatalytic terms for practical applications are elucidated.