N , N ′-Dimethylurea as an efficient ligand for the synthesis of pharma-relevant motifs through Chan–Lam cross-coupling strategy

The combination of copper and N , N ′-dimethylurea is used to showcase the Chan–Lam N -arylation of three different nitrogen nucleophiles. The synthesized catalyst is cheap, chemoselective, and also found to be effective in the N -arylation of target APIs.