Taurine mitigates bisphenol A-induced maternal–fetal oxidative stress and improves fetal weight by regulating Nrf2-Keap1 pathway, gut microbiota and bile acid metabolism
Lei Xu, Chenggang Yin, Yuyang Fan, Jiaqi Yang, Dongxu Ming, yanpin Li, Wenjuan Sun, Xilong Li 等 9 位
Chinese Academy of Agricultural Sciences Feed Research Institute Ministry of Agriculture and Rural Affairs
内容与影响
, and improving BA metabolic imbalance, thereby normalizing the "liver-gut microbiota-BA" metabolic axis. Our findings indicate that taurine mitigates BPA-induced maternal-fetal toxicity by targeting the microbiota-BA-oxidative stress axis. This study highlights taurine as a promising nutritional intervention strategy for protecting pregnancy against environmental toxicant exposure.
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物理Effects and risks of endocrine disrupting chemicals
Aldose Reductase and Taurine · Toxic Organic Pollutants Impact