Active shielding to reduce low frequency disturbances in direct current near biomagnetic measurements

Measurements of dc near biomagnetic fields are disturbed by low frequency noise that is not reduced sufficiently by most of the magnetically shielded rooms or gradiometers. For this reason an active shielding system has been developed at the Biomagnetic Center of the University of Jena. This work describes the principle of the active shielding system and demonstrates its properties concerning the attenuation of disturbing fields, frequency range, and some applications in biomedical measurements. We achieved a reduction of external low frequency magnetic fields by more than 50 dB and an attenuation of the field gradient by about 25 dB. This active shielding enables measurements of near dc biomagnetic fields in investigations of periinfarct depolarizations after ischemic stroke and spreading depression in migraine patients.