The effect of bispectral index guided anesthesia versus standard practice on recovery after sevoflurane anesthesia in children: a prospective randomized double-blind clinical trial

Background and aim Using bispectral index (BIS) guided anaesthesia may affect the quality of recovery and consumption of inhalational anaesthetic agents. The target of our study aimed to evaluate the impact of BIS-guided anaesthesia when compared with standard clinical practice to investigate the quality of recovery and sevoflurane concentration.Patients and method 54 children (aged3-12 years) go through ambulatory surgery that they randomized to receive sevoflurane anaesthesia controlled either merely by clinical parameters (controlled group), BIS-guided group within the BIS range of 40–60 (BIS group). The primary outcome has recorded the recovery time. The secondary outcome recorded the quality of recovery, which was measured by the Pediatric Anesthesia Emergence Delirium score.Results There were no statistically significant differences between Group C and Group BIS as regard age, weight, time of surgery, Time of anaesthesia, sex, ASA, type of surgery, mean value of PAED score at 20,25 and 30 min., heart rate and MAP. On the other hand, there were statistically significant differences between Group C and Group BIS as regarding Time for removal of the laryngeal mask, discharge to PACU, PACU time, PAED score at Baseline, 5, 10 and 15 min., and end-tidal sevoflurane concentration.Conclusion Sevoflurane anaesthesia guided by BIS results in decreased recovery and decreased sevoflurane concentration without affecting the quality of recovery in children go through ambulatory surgery.