研究论文
A Facile Synthesis of 3‐Substituted Phthalides
Li Guo, Dali Yin, Xiao‐Tian Liang
Chinese Academy of Medical Sciences & Peking Union Medical College
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摘要与影响
摘要 · 完整
1(3H)‐Isobenzofuranone (phthalides) and its derivatives possess a wide range of biological activities. A new method was found for the synthesis of 3‐substituted phthalides featured with the convenient condensation reaction of 3‐ethoxyphthalide with carbanions in high yields.
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学术脉络
学科主题
化学Organic Chemistry Synthesis Methods
Chemical synthesis and pharmacological studies · Advanced Synthetic Organic Chemistry
参考文献 15
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Synthetic Applications of Dealkoxycarbonylations of Malonate Esters, β-Keto Esters, α-Cyano Esters and Related Compounds in Dipolar Aprotic Media - Part I
被引 389A. Paul Krapcho · Synthesis · 1982
Central nervous system active compounds. XII. The synthesis and properties of 3-dimethylaminomethylene phthalides
被引 8S. I. CLARKE, B. KASUM, RH Prager · Australian Journal of Chemistry · 1983
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引用本文 14
Recent advancements in synthetic methodologies of 3-substituted phthalides and their application in the total synthesis of biologically active natural products
被引 70Amardeep Awasthi, Mandeep Singh, Garima Rathee · RSC Advances · 2020
Regio‐ and Stereoselective Synthesis of (Z)‐ 3‐Ylidenephthalides via H3PMo12O40‐Catalyzed Cyclization of 2‐Acylbenzoic Acids with Benzylic Alcohols
被引 36Guo‐Ping Yang, Ke Li, Xiaoling Lin · Chinese Journal of Chemistry · 2021
The Krapcho Dealkoxycarbonylation Reaction of Esters with α‐Electron‐Withdrawing Substituents
被引 16A. Paul Krapcho, Engelbert Ciganek · Organic reactions · 2013
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