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AMPK → ULK1 → Autophagy
Peter J. Roach
Indiana University School of Medicine Indiana University – Purdue University Indianapolis
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摘要与影响
摘要 · 完整
Several recent papers (2, 6, 7, 13) have addressed a new mechanism for the control of mammalian autophagy by the AMP-activated protein kinase (AMPK). Autophagy describes a family of highly conserve...
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学术脉络
学科主题
生物医学Metabolism, Diabetes, and Cancer
Pancreatic function and diabetes · Autophagy in Disease and Therapy
参考文献 17
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
被引 7,151Joungmok Kim, Mondira Kundu, Benoı̂t Viollet · Nature Cell Biology · 2011
Mammalian autophagy: core molecular machinery and signaling regulation
被引 1,966Zhifen Yang, Daniel J. Klionsky · Current Opinion in Cell Biology · 2009
Dynamics and diversity in autophagy mechanisms: lessons from yeast
被引 1,736Hitoshi Nakatogawa, Kuninori Suzuki, Yoshiaki Kamada · Nature Reviews Molecular Cell Biology · 2009
此处列出前 3 条
引用本文 150
Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
被引 1,482Sebastian Alers, Antje S Löffler, Sebastian Wesselborg · Molecular and Cellular Biology · 2011
Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies
被引 835Md Entaz Bahar, Hyun Joon Kim, Deok Ryong Kim · Signal Transduction and Targeted Therapy · 2023
Gastric cancer: a comprehensive review of current and future treatment strategies
被引 803Rachel Sexton, Mohammed Najeeb Al Hallak, Maria Diab · Cancer and Metastasis Reviews · 2020
按被引量排序,此处列出前 3 条