研究论文开放获取
FXR Signaling-Mediated Bile Acid Metabolism Is Critical for Alleviation of Cholesterol Gallstones by Lactobacillus Strains
Xin Ye, Dan Huang, Zhixia Dong, Xiaoxin Wang, Min Ning, Jie Xia, Shuang Shen, Shangong Wu 等 11 位
Shanghai Jiao Tong University Shanghai Sixth People's Hospital Shanghai First People's Hospital
来源Microbiology Spectrum
年份2022
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摘要与影响
摘要 · 完整
strains prevented CGS formation by fully activating the hepatic and ileal FXR signaling pathways. They could be a promising therapeutic strategy for treating CGS or preventing its recurrence.
逐年被引趋势
21110
22
23
2124
25
26
关键指标
67
被引次数 · OpenAlex
11.64
领域内被引倍数
同类平均 = 1
同类平均 = 1
前 0.8%
引用位次
同领域 · 同年份 · 同类型
同领域 · 同年份 · 同类型
70
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学术脉络
学科主题
生物医学Pediatric Hepatobiliary Diseases and Treatments
Pancreatic and Hepatic Oncology Research · Pancreatitis Pathology and Treatment
参考文献 70
Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis
被引 67Jin Chai, Shi‐Ying Cai, Xiaocong Liu · Journal of Hepatology · 2015
Bile acid synthesis in humans: Regulation of hepatic microsomal cholesterol 7α-hydroxylase activity
被引 109Eva Reihnér, Ingemar Björkhem, Bo Angelin · Gastroenterology · 1989
The role of the gallbladder in the pathogenesis of cholesterol gallstones
被引 141Wayne W. LaMorte, David J. Schoetz, Desmond H. Birkett · Gastroenterology · 1979
此处列出前 3 条
引用本文 67
FXR agonists for MASH therapy: Lessons and perspectives from obeticholic acid
被引 111Kang Wang, Yuecan Zhang, Guangji Wang · Medicinal Research Reviews · 2023
Probiotics and Non-Alcoholic Fatty Liver Disease: Unveiling the Mechanisms of Lactobacillus plantarum and Bifidobacterium bifidum in Modulating Lipid Metabolism, Inflammation, and Intestinal Barrier Integrity
被引 69Jing Lu, Dilireba Shataer, Huizhen Yan · Foods · 2024
Gastrointestinal microbiome and cholelithiasis: Current status and perspectives
被引 53Wan-Yue Dan, Yun-Sheng Yang, Li-Hua Peng · World Journal of Gastroenterology · 2023
按被引量排序，此处列出前 3 条