高能量饮食及肥胖影响男性生育力的研究进展

The implications of high-energy diet and obesity on male infertility have garnered significant attention. Numerous studies have emphasized the pivotal roles of high-energy diet and obesity in male infertility, impacting the male reproductive axis, semen quality, gut microbiota, and testicular microenvironment. Paternal obesity affects the health of the offspring through epigenetic modifications in sperm. Nonetheless, improving dietary structure and implementing appropriate weight loss measures can partially alleviate the adverse effects of high-energy diet and obesity on male infertility. This review aims to summarize the current research progress on the relationship between high-energy diet, obesity, and male infertility; investigate the underlying mechanisms leading to male infertility, and explore potential intervention strategies to enhance male reproductive health.