Psychological Inflexibility, Mindfulness, Emotion Regulation, Self-compassion, and Anxiety in Adults: A Serial Mediation Model

This study examines the mediating roles of mindfulness, emotion regulation, and self-compassion in the relationship between psychological inflexibility and anxiety in adults. The research was conducted within the scope of a quantitative study using a cross-sectional design, and data were collected from 443 university students. Participants completed validated measurement instruments assessing psychological inflexibility, mindfulness, emotion regulation, self-compassion, and anxiety. Mediation analyses revealed that psychological inflexibility significantly predicted higher levels of anxiety and that this relationship was partially mediated by mindfulness, emotion regulation, and self-compassion. Specifically, psychological inflexibility was found to increase difficulties in emotion regulation and negatively affect mindfulness and self-compassion, which in turn contributed to higher anxiety levels. These findings highlight the importance of targeting psychological flexibility, mindfulness, emotion regulation, and self-compassion in clinical interventions aimed at reducing anxiety. The results provide empirical support for acceptance-based interventions, such as Acceptance and Commitment Therapy, in promoting psychological well-being.