A Review on the Valorization of Lignocellulosic Biomass for Succinic Acid Production: Strengths and Weaknesses

Bio-based succinic acid production holds great promise for the process sustainability through the use of renewable resources such as lignocellulosic biomass and the use of microorganisms that can utilize CO2 in fermentation processes. A critical review of the latest findings on succinic acid production from lignocellulosic biomass was discussed, by highlighting all the key aspects of optimization processes at different levels of the process from pre-treatment to succinic acid production. Chemical-physical pretreatments seemed to be the most appropriate for the pretreatment of lignocellulosic biomass, but many strategies are still needed to solve the problem of variability in initial composition, the presence of post-treatment inhibitory compounds and the use of green solvent. In addition, the saccharization-fermentation process seemed to be the most suitable for the fermentative process of hydrolysates obtained from pretreatment to produce bio-based succinic acid. Certainly new studies and strategies are still needed to overcome the weaknesses of the whole process of succinic acid production from lignocellulosic biomass.