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Association Between Clonal Hematopoiesis of Indeterminate Potential and Brain β-Amyloid Deposition in Korean Patients With Cognitive Impairment
Jiwon Yun, Young Chul Youn, Hye Ryoun Kim
Korea University Chung-Ang University
来源Annals of Laboratory Medicine
年份2024
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and the C:G>T:A single-nucleotide variants were identified as the primary characteristics, which reflect aged hematopoiesis in the study population. Multivariate logistic regression revealed that the presence of CHIP was not associated with brain Aβ deposition. As both CHIP and brain Aβ deposition are associated with aging, further research is required to elucidate their possible interplay.
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生物医学Acute Myeloid Leukemia Research
Epigenetics and DNA Methylation · Cancer Genomics and Diagnostics
参考文献 17
Mild Cognitive Impairment
被引 1,301Ronald C. Petersen · New England Journal of Medicine · 2011
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
被引 1,973David P. Steensma, Rafael Bejar, Siddhartha Jaiswal · Blood · 2015
A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
被引 3,134Frank Jessen, Rebecca E. Amariglio, Martin P.J. van Boxtel · Alzheimer s & Dementia · 2014
此处列出前 3 条
引用本文 5
Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases
被引 3Jinglei Zhang, Shuo-Lan Tong, Qiqi Zhuang · Military Medical Research · 2025
Clonal Hematopoiesis of Indeterminate Potential as an Emerging Interdisciplinary Risk Factor in Alzheimer’s Disease: Current Evidence and Future Directions
被引 0Klara Kopp, Patricia Silva, Frederik Damm · Biomedicines · 2026
An attempt to personalize approaches to the treatment of patients with amyotrophic lateral sclerosis: analysis of immunological parameters of bone marrow cells and clonal hematopoiesis
被引 0И. С. Долгополов, Л. Ю. Гривцова, N. I. Kovalenko · Russian Journal for Personalized Medicine · 2025
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