力致发光材料的发光机理及生物医学应用研究进展

Since the discovery of mechanoluminescence， it has undergone decades of development and has been widely applied in various fields， including sensing， anti-counterfeiting， and structural detection.However， the application of mechanoluminescent materials in biomedical fields is still in its early stages， with relatively few reports available.This paper first introduces advanced strategies for synthesizing mechanoluminescent materials and system • atically discusses several typical mechanoluminescence mechanisms， with a focus on trap-controlled mechanolumi• nescence.Additionally， it presents the recently developed novel mechanoluminescence models based on chemilumi• nescence and bioluminescence.Furthermore， this paper provides a comprehensive overview of the applications of mechanoluminescent materials in biomedical fields， including biosensing， near-infrared bioimaging， optogenetic neuromodulation， and disease treatment.Lastly， this paper summarizes the major challenges faced by mechanolumi• nescent materials in biomedical applications and proposes their future research directions.