Effects of Nurse-Led Multidisciplinary Holistic Nonpharmacological Interventions on Fatigue in Hemodialysis Patients: A Randomized Controlled Trial

Fatigue is a common and debilitating symptom among patients undergoing hemodialysis, often causing both mental and physical exhaustion that negatively affects daily functioning, social engagement, and overall quality of life. Despite its impact, the significance of fatigue in this population is often underrecognized, and strategies for its management remain limited. Most prior studies have focused primarily on physical fatigue, with limited consideration of mental fatigue. This study aimed to ev