The Formation, Mechanism and Biochemistry of MDA and MDA as a Biomarker of Oxidative Stress

Malondialdehyde (MDA) is most frequently used biomarker of oxidative stress in many health problems such as cancer, psychiatry, chronic obstructive pulmonary disease, asthma, or cardiovascular diseases. In finding the oxidative stress MDA is used as a reliable biomarker. MDA is found in high levels in patients that suffer with goiter. MDA determination can take place by different methods. The determination of MDA was studied in goiter patients through a simple, and rapid but sensitive scientific method. This review is aimed to study the biochemical mechanism of formation of maliondialdehyde and the role of Maliondialdehyde as a biomarker for the diagnosis of several biochemical competition.